Projects

Optimizing the Biology of the Animal-Plant Interface for Improved Sustainability of Forage-Based Animal Enterprises Appropriated (D)   Accession Number: 423805

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Steer and pasture responses for a novel endophyte tall fescue developed for the upper transition zone - (Peer Reviewed Journal) - (29-Dec-11)

Constriction of bovine vasculature by endophyte-infected tall fescue seed extract is similar to pure ergovaline - (Peer Reviewed Journal)

Foote, A.P., Harmon, D.L., Brown, K.R., Strickland, J.R., Mcleod, K.R., Bush, L.P., Klotz, J.L. 2012. Constriction of bovine vasculature by endophyte-infected tall fescue seed extract is similar to pure ergovaline. Journal of Animal Science. 90:1603-1609.

Evaluation of a ruminally dosed tall fescue seed extract as a model for fescue toxicosis in steers - (Peer Reviewed Journal)

Koontz, A.F., Bush, L.P., Klotz, J.L., Mcleod, K.R., Schrick, F.N., Harmon, D.L. 2012. Evaluation of a ruminally dosed tall fescue seed extract as a model for fescue toxicosis in steers. Journal of Animal Science. 90:914-921.

Protein degradation of smooth bromegrass switchgrass and big bluestem in grazing cattle - (Peer Reviewed Journal) - (03-May-11)

Disrupted hair follicle activity in cattle grazing endophyte-infected tall fescue in the summer insulates core body temperatures - (Peer Reviewed Journal)

Aiken, G.E., Klotz, J.L., Looper, M.L., Tabler, S.F., Schrick, F.N. 2011. Disrupted hair follicle activity in cattle grazing endophyte-infected tall fescue in the summer insulates core body temperatures. Professional Animal Scientist. 27:336-343.

Effect of ergot alkaloids on contractility of bovine right ruminal artery and vein - (Peer Reviewed Journal)

Foote, A.P., Harmon, D.L., Strickland, J.R., Bush, L.P., Klotz, J.L. 2011. Effect of ergot alkaloids on contractility of bovine right ruminal artery and vein. Journal of Animal Science. 89:2944-2949.

Contractile response of bovine lateral saphenous vein to ergovaline serotonin2A a2A- and a2C-adrenergic receptor agonists relative to time off endophyte-infected tall fescue - (Abstract Only)

Klotz, J.L., Aiken, G.E., Foote, A.P., Bush, L.P., Brown, K.R., Goff, B.M., Strickland, J.R. 2011. Contractile response of bovine lateral saphenous vein to ergovaline serotonin2A a2A- and a2C-adrenergic receptor agonists relative to time off endophyte-infected tall fescue. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 89(E-Suppl. 1):50.

Endophyte-infected tall fescue seed extract induces constriction of bovine vasculature - (Abstract Only)

Foote, A.P., Harmon, D.L., Brown, K.R., Strickland, J.R., Mcleod, K.R., Bush, L.P., Klotz, J.L. 2011. Endophyte-infected tall fescue seed extract induces constriction of bovine vasculature. Joint Meeting of the ADSA, AMSA, ASAS and PSA. 89(E-Suppl. 1):49-50.

Ergot alkaloids: toxicokinetics and vascular effects - (Book / Chapter)

Strickland, J.R., Brown, K.R., Aiken, G.E., Klotz, J.L., Flythe, M.D. 2012. Ergot alkaloids: toxicokinetics and vascular effects. International Symposium on Fungal Endophytes of Grasses. pgs 14-19.

A vascular contractility bioassay using bovine right ruminal artery and vein - (Peer Reviewed Journal)

Klotz, J.L., Bush, L.P., Strickland, J.R. 2011. A vascular contractility bioassay using bovine right ruminal artery and vein. Journal of Animal Science. 89:1944-1951.

Tall Fescue Alkaloids Bind Serotonin Receptors in Cattle - (Experiment Station)

Klotz, J.L., Strickland, J.R., Bush, L.P., Brown, K.R., Aiken, G.E. 2010. Tall Fescue Alkaloids Bind Serotonin Receptors in Cattle. Kentucky Beef Report. pgs 37-43.

Effect of Ergot Alkaloids on Bovine Foregut Vasculature - (Experiment Station)

Foote, A.P., Klotz, J.L., Harmon, D.L., Bush, L.P., Strickland, J.R. 2010. Effect of Ergot Alkaloids on Bovine Foregut Vasculature. Kentucky Beef Report. pgs 33-36.

Ergot Alkaloids: Toxicokinetics and Vascular Effects in Grazing Animals - (Abstract Only)

Strickland, J.R., Aiken, G.E., Klotz, J.L., Flythe, M.D., Brown, K.R. 2010. Ergot Alkaloids: Toxicokinetics and Vascular Effects in Grazing Animals. International Symposium on Fungal Endophytes of Grasses. pp 103-104.

An Extract of Endophyte Infected Tall Fescue Seed Induces Vasoconstriction of Bovine Foregut Vasculature - (Abstract Only)

Foote, A.P., Klotz, J.L., Bush, L.P., Strickland, J.R., Harmon, D.L. 2010. An Extract of Endophyte Infected Tall Fescue Seed Induces Vasoconstriction of Bovine Foregut Vasculature. International Symposium on Fungal Endophytes of Grasses. pp 33-34.

Efficacy of a Fescue Seed Extract in Inducing Toxicosis in Cattle - (Abstract Only)

Koontz, A.F., Bush, L.P., Klotz, J.L., Mcleod, K.R., Harmon, D.L. 2010. Efficacy of a Fescue Seed Extract in Inducing Toxicosis in Cattle. International Symposium on Fungal Endophytes of Grasses. p 58.

A Simple Tall Fescue Seed Extraction and Partial Purification of Ergovaline - (Abstract Only)

Fannin, F., Ji, H., Klotz, J.L., Bush, L.P. 2010. A Simple Tall Fescue Seed Extraction and Partial Purification of Ergovaline. International Symposium on Fungal Endophytes of Grasses. p 31.

Antagonism of 5-hydroxytryptamine2A Receptor Results in Decreased Contractile Response of Bovine Lateral Saphenous Vein to Tall Fescue Alkaloids - (Abstract Only)

Klotz, J.L., Strickland, J.R., Bush, L.P., Kirch, B.H., Brown, K.R. 2010. Antagonism of 5-hydroxytryptamine2A Receptor Results in Decreased Contractile Response of Bovine Lateral Saphenous Vein to Tall Fescue Alkaloids. J. Anim. Sci. Vol. 88, E-Suppl. 2/J. Dairy Sci. Vol. 93, E-Suppl. 1/Poult. Sci. Vol. 89, E-Suppl. 1. pg 55.

Ergot alkaloids induce vasoconstriction of bovine foregut vasculature - (Abstract Only)

Foote, A.P., Klotz, J.L., Harmon, D.L., Bush, L.P., Strickland, J.R. 2010. Ergot alkaloids induce vasoconstriction of bovine foregut vasculature. J. Anim. Sci. 88( 2/J). Dairy Sci. Vol. 93(1)/Poult. Sci. 89(1):701.

Development of a fescue toxicosis model using a fescue seed extract - (Abstract Only)

Koontz, A.F., Bush, L.P., Klotz, J.L., Mcleod, K.R., Schrick, F.N., Harmon, D.L. 2010. Development of a fescue toxicosis model using a fescue seed extract. J. Anim. Sci. 88:(2/J). Dairy Sci. 93( 1)/Poult. Sci. 89(1):704.

Tall fescue alkaloids cause vasoconstriction in equine medial palmar artery and vein - (Abstract Only)

Klotz, J.L., Mcdowell, K.J. 2010. Tall fescue alkaloids cause vasoconstriction in equine medial palmar artery and vein. J. Anim. Sci. 88(2/J). Dairy Sci. 93(1)/Poult. Sci. 89(1):55.

Contractile response of fescue-naïve bovine lateral saphenous veins to increasing concentrations of tall fescue alkaloids - (Peer Reviewed Journal)

Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R. 2009. Contractile Response of Fescue-Naïve Bovine Lateral Saphenous Veins to Increasing Concentrations of Tall Fescue Alkaloids. J Anim Sci. 88:408-415.

USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop) - (Other)

Klotz, J.L., Bush, L.P., Strickland, J.R., West, C.P., Dinkins, R.D. 2009. USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop). SERA-IEG 8. p 62-66.

Development and validation of a LC-MS method for quantitation of ergot alkaloids in lateral saphenous vein tissue - (Peer Reviewed Journal)

Smith, D.L., Smith, L.L., Shafer, W.D., Klotz, J.L., Strickland, J.R. 2009. Development and validation of a LC-MS method for quantitation of ergot alkaloids in lateral saphenous vein tissue. Journal of Agricultural and Food Chemistry. 57:7213-7220.

Ergot Alkaloid-Induced Blood Vessel Dysfunction Contributes to Fescue Toxicosis - (Peer Reviewed Journal)

Strickland, J.R., Aiken, G.E., Klotz, J.L. 2009. Ergot Alkaloid-Induced Blood Vessel Dysfunction Contributes to Fescue Toxicosis. Forage and Grazinglands. 4Nov09.

Bioaccumulation of Ergovaline in Bovine Lateral Saphenous Veins in Vitro - (Peer Reviewed Journal)

Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R. 2009. Bioaccumulation of Ergovaline in Bovine Lateral Saphenous Veins in Vitro. J Anim Sci. 2009. 87:2437-2447.

Validation of Right Ruminal Vein and Artery as Models of Bovine Foregut Vasculature - (Abstract Only)

Klotz, J.L., Bush, L.P., Strickland, J.R. 2009. Validation of Right Ruminal Vein and Artery as Models of Bovine Foregut Vasculature. Joint Abstracts of the American Dairy Science and Society of Animal Science. 87,E-Supp 2. p.83(M257).

USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop) - (Other)

Klotz, J.L., Smith, L.L., Bush, L.P., Strickland, J.R. 2008. USDA - Kentucky Report (Annual Report to SERA-IEG 8, Tall Fescue Toxicosis/Endophyte Workshop). SERA-IEG 8. pgs 54-58.

Tennessee Report (Annual Report to SERA-IEG8 Tall Fescue Toxicosis/Endophyte Workshop) - (Other)

Norman, R., Lane, C.D., Fisher, A.E., Campbell, B.T., Schrick, F.N., Waller, J.C., Block, S.S., Kojima, C.J., Spiers, D.E., Klotz, J.L., Strickland, J.R., Bates, G.E., Riggins, J.C., Hopkins, F.M., Edwards, J.L., Prado, T. 2008. Tennessee Report (Annual Report to SERA-IEG8 Tall Fescue Toxicosis/Endophyte Workshop). SERA-IEG 8. Meeting Report pgs 110-121.

Growing steers grazing high versus low endophyte (Neotyphodium coenophialum)-infected tall fescue have reduced serum enzymes increased hepatic glucogenic enzymes and reduced liver and carcass mass - (Peer Reviewed Journal)

Brown, K.R., Anderson, G.A., Son, K., Rentfrow, G., Bush, L.P., Klotz, J.L., Strickland, J.R., Boling, J.A., Matthews, J.C. 2009. Growing steers grazing high versus low endophyte (Neotyphodium coenophialum)-infected tall fescue have reduced serum enzymes, increasedhepatic glucogenic enzymes, and reduced liver and carcass tissue mass. J. Anim. Sci. 87:748-760.

Technical note: comparison between two tracing methods with ultrasonography to determine lumen area of the caudal artery in beef cattle - (Peer Reviewed Journal)

Aiken, G.E., Klotz, J.L., Kirch, B.H., Strickland, J.R., Boykin, D.L. 2008. Technical note: Comparison between two tracing methods with ultrasonography to determine lumen area of the caudal artery in beef cattle. Journal of Animal Science. 87:371-374.

Grazing Endophyte-Infected Tall Fescue Alters Serotonin Receptor-Induced Contractility of Bovine Lateral Saphenous Veins - (Abstract Only)

Klotz, J.L., Brown, K.R., Xue, Y., Matthews, J.C., Boling, J.A., Bush, L.P., Strickland, J.R. 2008. Grazing Endophyte-Infected Tall Fescue Alters Serotonin Receptor-Induced Contractility of Bovine Lateral Saphenous Veins. J. Anim. Sci. Vol. 86. p 102.

Steers Grazing Toxic Neotyphodium Coenophialum-Infected Forages Have Increased Hepatic Gluconeogenic Capacity - (Abstract Only)

Brown, K.R., Klotz, J.L., Strickland, J.R., Bush, L.P., Boling, J.A., Matthews, J.C. 2008. Steers Grazing Toxic Neotyphodium Coenophialum-Infected Forages Have Increased Hepatic Gluconeogenic Capacity. J. .Anim. Sci. Vol. 86, E-Suppl. 2. p 101.

The Effect of Toxic Tall Fescue on Cellobiose-Utilizing Populations in the Bovine Rumen - (Abstract Only)

Flythe, M.D., Gellin, G.L., Klotz, J.L., Strickland, J.R., Brown, K.R., Matthews, J.C., Boling, J.A. 2008. The Effect of Toxic Tall Fescue on Cellobiose-Utilizing Populations in the Bovine Rumen. American Society for Microbiology Annual Meeting. ISBN 978-1555814939. Z-040 (Abstract CD).

Effects of Selected Combinations of Tall Fescue Alkaloids on the Vasoconstrictive Capacity of Fescue-Naive Bovine Lateral Saphenous Veins - (Peer Reviewed Journal)

Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R. 2008. Effects of Selected Combinations of Tall Fescue Alkaloids on the Vasoconstrictive Capacity of Fescue-Naive Bovine Lateral Saphenous Veins. Journal of Animal Science. 2008. 86:1021-1028.

Ergot Alkaloid Effects on Animal Physiology - (Abstract Only)

Strickland, J.R., Kirch, B.H., Klotz, J.L., Smith, L.L., Aiken, G.E., Flythe, M.D. 2008. Ergot Alkaloid Effects on Animal Physiology. Society for Range Management Meeting Abstracts. Published on Compact Disc, distributed at meeting; Abstract #1843. (http://srm.confex.com/srm/2008/techprogram/P1843.HTM).

USDA Kentucky Report - (Proceedings)

Strickland, J.R., Dinkins, R.D., Aiken, G.E., Klotz, J.L., Kirch, B.H., Smith, L.L., Barnes, A.J., Waters, W.J., Bush, L.P., Brown, K.R., Matthews, J.C., Boling, J.A. 2007. Usda Kentucky report. SERA-IEG 8. pgs 159-178.

Ergovaline-induced vasoconstriction in an isolated bovine lateral saphenous vein bioassay - (Peer Reviewed Journal)

Klotz, J.L., Bush, L.P., Smith, D.L., Shafer, W.D., Smith, L.L., Arrington, B.C., Strickland, J.R. 2007. Ergovaline-induced vasoconstriction in an isolated bovine lateral saphenous vein bioassay. Journal of Animal Science. 85:2330-2336.

Separation and Quantitation of Seven Ergot Alkaloids in Bovine Vein Tissue - (Abstract Only)

Shafer, W.D., Smith, D.L., Smith, L.L., Klotz, J.L., Strickland, J.R. 2007. Separation and Quantitation of Seven Ergot Alkaloids in Bovine Vein Tissue. Proceedings of the ASMS Conference on Mass Spectrometry and Allied Topics, June 3-7, 2007. #ThPh-118.

Ergocryptine and Ergonovine Induced Contractile Responses in Fescue Naive Bovine Lateral Saphenous Veins - (Abstract Only)

Klotz, J.L., Kirch, B.H., Aiken, G.E., Arrington, B.C., Bush, L.P., Strickland, J.R. 2007. Ergocryptine and Ergonovine Induced Contractile Responses in Fescue Naive Bovine Lateral Saphenous Veins. J. Anim. Sci. Vol. 85, Suppl. 1/J. Dairy Scit. Vol. 90, SUppl. 1/Poult. Sci. Vol. 86 Suppl 1. pg 13.

Grazing High Versus Low Endophyte-Infected Tall Fescue Reduces Contractility of Bovine Lateral Saphenous Veins - (Abstract Only)

Klotz, J.L., Brown, K.R., Matthews, J.C., Boling, J.A., Bush, L.P., Strickland, J.R. 2007. Grazing High Versus Low Endophyte-Infected Tall Fescue Reduces Contractility of Bovine Lateral Saphenous Veins. J. Anim. Sci. Vol. 85, Suppl. 1/J. Dairy Scit. Vol. 90, SUppl. 1/Poult. Sci. Vol. 86 Suppl 1. pg 12-13.

Neotyphodium Coenophialum Alters Blood Metabolites Involved in Nitrogen, Energy, and Minteral Metabolism in Growing Steers - (Abstract Only)

Brown, K.R., Harrison, L.R., Klotz, J.L., Strickland, J.R., Boling, J.A., Matthews, J.C. 2007. Neotyphodium Coenophialum Alters Blood Metavolites Involved in Nitrogen, Energy, and Minteral Metabolism in Growing Steers. J. Anim. Sci. Vol. 85, Suppl. 1/J. Dairy Scit. Vol. 90, SUppl. 1/Poult. Sci. Vol. 86 Suppl 1. pg 418.

Changes in net portal nutrient flux in response to weaning transition and lonohore supplementation in dairy calves - (Peer Reviewed Journal)

Klotz, J.L., Heitmann, R.N. 2007. Changes in net portal nutrient flux in response to weaning transition and lonohore supplementation in dairy calves. Journal of Dairy Science. 90:1326-1339.

USDA-Kentucky Report: Forage-Animal Production Research Unit (FAPRU) Investigations: Tall Fescue Alkaloids and Toxicosis - (Proceedings)

Strickland, J.R., Aiken, G.E., Dinkins, R.D., Klotz, J.L., Kirch, B.H., Smith, L.L., Looper, M.L., Bush, L.P., Arrington, B.C., Smith, D.L., Shafer, W.D., Schardl, C., Hesse, U. 2006. Usda-Kentucky Report: Forage-Animal Production Research Unit (FAPRU) Investigations: Tall Fescue Alkaloids and Toxicosis. SERA-IEG 8. Annual Report: pgs. 97-111.

Assessment of Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Lateral Saphenous Veins of Crossbreed Heifer Cattle - (Proceedings)

Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Strickland, J.R., Arrington, B.C. 2007. Assessment of Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Lateral Saphenous Veins of Crossbreed Heifer Cattle. Proceedings of the 6th International Symposium on Fungal Endophytes of Grasses. Grassland Research and Practice Series No. 13:383-385.

ASSESSMENT OF VASOCONSTRICTIVE POTENTIAL OF D-LYSERGIC ACID USING AN ISOLATED BOVINE LATERAL SAPHENOUS VEIN BIOASSAY - (Peer Reviewed Journal)

Klotz, J.L., Bush, L.P., Smith, D.L., Schafer, W.D., Smith, L.L., Vevoda, A.O., Craig, A.M., Arrington, B.C., Strickland, J.R. 2006. Assessment of vasoconstrictive potential of d-lysergic acid using an isolated bovine lateral saphenous vein bioassay. Journal of Animal Science. 84:3167-3175.

MONITORING THE PRESENCE OF ERGOT ALKALOIDS IN FORAGE ANIMAL SAMPLES - (Other)

Smith, D.L., Shafer, W.D., Smith, L.L., Klotz, J.L., Strickland, J.R. 2006. Monitoring the presence of ergot alkaloids in forage animal samples. American Society for Mass Spectrometry. Proceedings of the 54th ASMS Conference.

GROSS AND HISTOPATHOLOGICAL OBSERVATIONS OF LONG TERM CATHETERIZED VESSELS IN EXPERIMENTAL SHEEP - (Peer Reviewed Journal)

Barraza, M.L., Strickland, J.R., Zepada, H., Taylor, J.B., Krehbiel, C.R., Bell, G.S., Koltz, J.L., 2006. Gross and histopathological observations of long term catheterized vessels in experimental sheep. Journal of Veterinary Medicine. 53:230-238 (2006).

Evaluation of the Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Bovine Lateral Saphenous Veins - (Abstract Only)

Klotz, J.L., Kirch, B.H., Aiken, G.E., Bush, L.P., Arrington, B.C., Strickland, J.R. 2006. Evaluation of the Vasoconstrictive Capacity of Tall Fescue Alkaloids Using Fescue Naive Bovine Lateral Saphenous Veins. Journal of Animal Science Supplement. 84:54.

Response of Bovine Lateral Saphenous Vein to Increasing Concentrations of Lysergic Acid and Ergovaline - (Abstract Only)

Klotz, J.L., Arrington, B.C., Bush, L.P., Strickland, J.R. 2006. Response of Bovine Lateral Saphenous Vein to Increasing Concentrations of Lysergic Acid and Ergovaline. Journal of Animal Science Supplement. 84:53-54.

EFFECTS OF WEANING AND INOPHORE SUPPLEMENTATION ON SELECTED BLOOD METABOLITES AND GROWTH IN DAIRY CALVES - (Peer Reviewed Journal)

Klotz, J.L., Heitmann, R.N. 2006. Effects of weaning and inophore supplementation on selected blood metabolites and growth in dairy calves. Journal of Dairy Science. 89:3587-3598.

ANNUAL PROGRESS REPORT FOR USDA-ARS-FAPRU TO SERAIEG 8 TALL FESCUE TOXICOSIS/ENDOPHYTE WORKSHOP - (Other)

Klotz, J.L., Schafer, W.D., Smith, D.K., Smith, L.L., Arrington, B.C., Bush, L.P., Strickland, J.R., Aiken, G.E., Schardl, S., Hesse, U., Dinkins, R.D. 2005. Annual progress report for USDA-ARS-FAPRU to SERA-IEG 8 Tall Fescue Toxicosis/Endophyte Workshop. Meeting Proceedings. pgs 30-36.

Clearance of Para-Aminohippuric Acid in Wethers Consuming Locoweed - (Peer Reviewed Journal)

Strickland, J.R., Custis, M., Ashley, A.K., Smith, L.L., Klotz, J.L., Krehbiel, C. 2005. Clearance of Para-Aminohippuric Acid in Wethers Consuming Locoweed. New Zealand Veterinary Journal. 53(5):288-292.

Effects of Limb Origin and Twenty-four Hour Storage on Contractile Response of Bovine Lateral Saphenous Vein to Norepinephrine - (Abstract Only)

Klotz, J.L., Sevold, A., Bush, L., Strickland, J.R. 2005. Effects of Limb Origin and Twenty-four Hour Storage on Contractile Response of Bovine Lateral Saphenous Vein to Norepinephrine. Journal of Animal Science. 83:299.