Projects

DIET AND IMMUNE FUNCTION RELATED TO INFECTIOUS AND ALLERGIC DISEASE Appropriated (D)   Accession Number: 416839

MOLECULAR AND CELLULAR BASES OF HEALTH-PROMOTING FOOD COMPONENTS IN PREVENTION OF CHRONIC DISEASES Appropriated (D)   Accession Number: 416843

PROBIOTIC-RELATED HEALTH RESEARCH Memorandum of Understanding (M)   Accession Number: 416726

SAFETY OF BIFIDOBACTERIUM LACTIS (BB12)SUPPLEMENTED YOGURT FOR ADULTS ON ANTIBIOTICS Nonfunded Cooperative Agreement (N)   Accession Number: 416866

IDENTIFICATION OF CHANGES IN IMMUNE BIOMARKERS AND MICROFLORA OF CHILDREN WITH ASTHMA AND ATOPY Nonfunded Cooperative Agreement (N)   Accession Number: 416872

MOLECULAR CHARACTERIZATION OF MICROBIOTA AND ITS RELATIONSHIP TO THE PREVALENCE OF VIRAL AND BACTERIAL ENTERITIS Nonfunded Cooperative Agreement (N)   Accession Number: 416927

OPEN LABEL STUDY TO EVALUATE THE SAFETY OF LACTOBACILLUS RHAMNOSUS GG ATCC 53103 IN HEALTHY VOLUNTEERS Reimbursable (R)   Accession Number: 420658

APPLICATION OF BIOINFORMATICS TO MICROFLORA OF OBESE PIGS Specific Cooperative Agreement (S)   Accession Number: 418291

EFFECTS OF MILK FAT ON OBESITY-MEDIATED CHANGES IN GASTROINTESTINAL FUNCTION AND MICROFLORA COMPOSITION Trust (T)   Accession Number: 422391

Publications (Clicking on the reprint icon will take you to the publication reprint.)

Development of a new PCR protocol to detect and subtype Blastocystis spp. from humans and animals - (Peer Reviewed Journal)

Santin, M., Gomez-Munoz, M., Solano Aguilar, G., Fayer, R. 2011. Development of a new PCR protocol to detect and subtype Blastocystis spp. from humans and animals. Parasitology Research. 109(1):205-212.

Safety assessment of probiotics for human use - (Review Article)

Sanders, M.E., Akkermans, L.M.A., Haller, D., Hammerman, C., Heimbach, J.T., Hormannsperger, G., Huys, G., Levy, D.D., Lutgendorff, F., Mack, D., Phothirath, P., Solano-Aguilar, G., Vaughan, E. 2010. Safety assessment of probiotics for human use. Gut Microbes. 1(3):164-185.

Localized Th1-, Th2-,and inflamation-associated hepatic and pulmonary immune responses in Ascaris-infected swine are increased by retinoic acid. - (Peer Reviewed Journal)

Dawson, H.D., Solano Aguilar, G., Beal, M.E., Beshah, E., Vangimalla, V.R., Jones, E., Botero, S., Urban Jr, J.F. 2009. Localized Th1-, Th2-,and inflamation-associated hepatic and pulmonary immune responses in Ascaris-infected swine are increased by retinoic acid. Infection and Immunity. 77(6):2576-87.

Feeding Probiotic Bacteria To Swine Enhances Immunity To Ascaris Suum - (Proceedings)

Solano Aguilar, G., Shea-Donohue, T., Madden, K., Dawson, H.D., Jones, Y., Restrepo, M.P., Beshah, E., Urban Jr, J.F. 2007. Feeding probiotic bacteria to swine enhances immunity to Ascaris Suum. Veterinary Immunology International Symposium. p.110.

Interaction of Bifidobacterium animalis subspecies lactis (Bb 12) and Salmonella typhimurium in continuous-flow chemostatic culture - (Proceedings)

Harvey, R.B., Genovese, K.J., Droleskey, R.E., Andrews, K., Solano Aguilar, G. 2007. Interaction of Bifidobacterium animalis subspecies lactis (Bb 12) and Salmonella typhimurium in continuous-flow chemostatic culture. In: Proceedings of the 7th International Safepork Symposium, May 9-11, 2007, Verona, Italy. p. 291-294.

Interaction of Bifidobacterium animalis subspecies lactis (Bb12) and Salmonella typhimurium in continuous-flow chemostatic culture - (Proceedings)

Harvey, R.B., Genovese, K.J., Droleskey, R.E., Andrews, K., Solano Aguilar, G. 2007. Interaction of Bifidobacterium animalis subspecies lactis (Bb12) and Salmonella typhimurium in continuous-flow chemostatic culture. In: Proceedings of 7th International Safepork Symposium, May 9-11, 2007, Verona, Italy. p. 291-294.

BIOFIOBACTERIUM LACTIS ENHANCES TOLL-LIKE RECEPTOR (TLR) PATHWAY GENE EXPRESSION LOCALLY IN THE COLON AND ENHANCES GLUCOSE UPTAKE IN THE SMALL INTESTINE OF PIGS INFECTED WITH PARASITIC NEMATODE ASCARIS SUM. - (Proceedings)

Solano Aguilar, G., Dawson, H.D., Shea-Donohue, T., Madden, K., Jones, Y.L., Beshah, E., Restrepo, M., Schoene, N.W., Hare Jr, W.R., Urban Jr, J.F. 2006. Biofiobacterium lactis enhances toll-like receptor (tlr) pathway gene expression locally in the colon and enhances glucose uptake in the small intestine of pigs infected with parasitic nematode ascaris sum. American Society for Microbiology Proceedings. 106:45A.

BIFIDOBACTERIUM LACTIS AFFECTS IMMUNE DEVELOPMENT OF NEONATAL PIGS: A MODEL FOR NUTRIENT CONDITIONING IN INFANTS. - (Abstract Only)

Solano Aguilar, G., Dawson, H.D., Jones, Y.L., Schoene, N.W., Beshah, E., Restrepo, M., Hare, W., Urban Jr, J.F. 2006. Bifidobacterium lactis affects immune development of neonatal pigs: a model for nutrient conditioning in infants. Meeting Abstract.

EFFECT OF MILK SUPPLEMENTATION WITH LACTOBACILLUS BREVIS 1E1 ON JEJUNAL GENE EXPRESSION - (Abstract Only)

Brown, D., Davis, E., Bass, B., Lockhart, B., Rehberger, T., Solano Aguilar, G., Jones, E.A., Dawson, H.D., Maxwell, C. 2006. Effect of milk supplementation with lactobacillus brevis 1e1 on jejunal gene expression [abstract]. Federation of American Societies for Experimental Biology Conference. 20(5):A1057

RELATIONSHIP BETWEEN IMMUNE CELL PHENOTYPES AND PIG GROWTH IN A COMMERCIAL FARM - (Peer Reviewed Journal)

Galina-Pantoja, L., Solano Aguilar, G., Mellencamp, M.A., Bastiaansen, J., Cabrera, R., Lunney, J.K. 2006. Relationship between immune cell phenotypes and pig growth in a commercial farm. Animal Biotechnology. 17:81-98

LOCALIZED MULTI-GENE EXPRESSION PATTERNS SUPPORT AN EVOLVING TH1/TH2-LIKE PARADIGM IN RESPONSE TO INFECTION WITH TOXOPLASMA GONDII AND ASCARIS SUUM - (Peer Reviewed Journal)

Dawson, H., Beshah, E., Nishii, S., Solano-Aguilar, G., Morimoto, M., Zhao, A. Madden, K., Ledbetter, T., Dubey, J.P., Shea-Donohue, T., Lunney, J.K., and Urban, J. F. Jr. 2005. Localized multi-gene expression patterns support an evolving Th1/Th2-like paradigm in response to infections with Toxoplasma gondii and Ascaris suum. Infection and Immunity. 73(2):1116-1128.

INCREASED TH2-ASSOCIATED IMMUNITY IN ASCURIS-INFECTED SWINE TREATED WITH RETINOIC ACID - (Abstract Only)

Dawson, H.D., Jones, E.A., Beshah, E., Solano Aguilar, G., Urban Jr, J.F. 2005. Increased Th2-associated immunity in ascuris-infected swine treated with retinoic acid. [abstract]. Federation of American Societies for Experimental Biology Journal. 19:A1466.

MOLECULAR CLONING OF THE SWINE IL-4 RECEPTOR AND IL-13 RECEPTOR ALPHA 1 CHAINS: EFFECTS OF EXPERIMENTAL TOXOPLASMA GONDII, ASCARIS SUUM AND TRICHURIS SUIS INFECTIONS ON TISSUE MRNA LEVELS - (Peer Reviewed Journal)

Zarlenga, D.S., Dawson, H.D., Kringel, H., Solano Aguilar, G., Urban Jr, J.F. 2004. Molecular cloning of the swine IL-4 receptor and IL-13 receptor alpha 1 chains: effects of experimental toxoplasma gondii, ascaris suum and trichuris suis infections on tissue mrna levels. Veterinary Immunology and Immunopathology 101(3-4):223-234.

THE EFFECT OF PROBIOTIC BACTERIA ON THE IMMUNE SYSTEM OF WEANED PIGS MONITORED BY REAL TIME PCR - (Peer Reviewed Journal)

Solano Aguilar, G., Ledbetter, T., Dawson, H.D., Andrews, K., Harvey, R.B., Schoene, N., Urban Jr, J.F. 2004. The effect of probiotic bacteria on the immune system of weaned pigs monitored by Real time PCR. Proceedings 18th International Pig Veterinary Society Meeting, Hamburg, Germany, October 2004. p. 380.

MOLECULAR CLONING OF THE SWINE IL-4 RECEPTOR AND IL-13 RECEPTOR ALPHA 1 CHAINS: EFFECTS OF EXPERIMENTAL TOXOPLASMA GONDII, ASCARIS SUUM AND TRICHURIS SUIS INFECTIONS ON TISSUE MRNA LEVELS - (Peer Reviewed Journal)

Zarlenga, D.S., Dawson, H.D., Kringle, H., Solano Aguilar, G., Urban Jr, J.F. 2004. Molecular cloning of the swine il-4 receptor and il-13 receptor alpha 1 chains: effects of experimental toxoplasma gondii, ascaris suum and trichuris suis infections on tissue mrna levels. Veterinary Immunology and Immunopathology. 101(3-4):223-34 (2004)

THE EFFECT OF HUMAN DERIVED PROBIOTIC BACTERIA ON THE IMMUNE AND INTESTINAL FUNCTION OF PIGS - (Abstract Only)

Solano Aguilar, G., Dawson, H.D., Ledbetter, T., Shea Donohue, P.T., Schoene, N.W., Call, J.E., Beshah, E., Hare Jr, W.R., Urban Jr, J.F. 2003. The effect of human derived probiotic bacteria on the immune and intestinal function of pigs [abstract]. Allen D. Leman Swine Conference. 30:26.

HUMAN DERIVED PROBIOTIC BACTERIA SPECIES CAN REGULATE INTESTINAL RESPONSES TO PARASITIC NEMATODES IN PIGS - (Peer Reviewed Journal)

Solano Aguilar, G., Dawson, H.D., Ledbetter, T., Shea Donohue, P.T., Schoene, N.W., Call, J., Beshah, E., Hare Jr, W.R., and Urban Jr, J.F. 2004. Human derived probiotic bacteria species can regulate intestinal responses to parasitic nematodes in pigs. Veterinary Parasitology. 125:47-161.

THE EFFECTS OF DIETARY PROBIOTICS ON IMMUNITY TO ASCARIS SUUM IN PIGS - (Abstract Only)

Solano Aguilar, G., Dawson, H.D., Ledbetter, T., Shea Donohue, P.T., Schoene, N.W., Call, J., Beshah, E., Hare Jr, W.R., Urban Jr, J.F. 2003. The effects of dietary probiotics on immunity to ascaris suum in pigs [abstract]. Proceedings of American Association of Veterinary Parasitologists. Paper No. 56-54.

THE EFFECT OF DIETARY PROBIOTIC IN THE IMMUNE RESPONSE OF PIGS - (Abstract Only)

Solano Aguilar, G., Ledbetter, T., Dawson, H.D., Schoene, N.W., Urban Jr, J.F. 2003. The effect of dietary probiotic in the immune response of pigs [abstract]. 9th International Symposium on Digestive Physiology in Pigs. 2:69.

LIMITED EFFECT OF RECOMBINANT PORCINE INTERLEUKIN 12 ON PORCINE LYMPHOCYTES DUE TO A LOW LEVEL OF IL-12 BETA 2 RECEPTOR - (Peer Reviewed Journal)

Solano Aguilar, G., Zarlenga, D.S., Beshah, E., Gasbarre, L.C., Junker, D., Cochran, M., Dawson, H.D., Urban Jr, J.F., Lunney, J.K. 2002. Limited effect of recombinant porcine interleukin 12 on porcine lymphocytes due to a low level of il-12 beta 2 receptor. Veterinary Immunology and Immunopathology. 89:133-148 (2002)

FUNCTIONAL GENOMIC ASSESSMENT OF PORCINE DISEASE RESISTANCE: REAL TIME ASSAYS OF PORCINE IMMUNE GENE EXPRESSION - (Proceedings)

Dawson, H.D., Nishi, S., Beshah, E., Solano Aguilar, G., Zarlenga, D.S., Urban Jr, J.F., Lunney, J.K. 2002. Functional genomic assessment of porcine disease resistance: real time assays of porcine immune gene expression. World Congress of Genetics Applied in Livestock Production #13-41.

LIMITED EFFECT OF RECOMBINANT PORCINE INTERLEUKIN-12 ON PORCINE LYMPHOCYTESDUE TO A LOW EXPRESSION OF IL-12 BETA2 RECEPTOR - (Peer Reviewed Journal)

SOLANO AGUILAR, G., ZARLENGA, D.S., BESHAH, E., VENGROSKI, K., GASBARRE, L.C., JUNKER, D., COCHRAN, M., WESTON, C., VALENCIA, D., LUNNEY, J.K. LIMITED EFFECT OF RECOMBINANT PORCINE INTERLEUKIN-12 ON PORCINE LYMPHOCYTESDUE TO A LOW EXPRESSION OF IL-12 BETA2 RECEPTOR. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY. vol. 89, pp. 133-48, 2002.

LOCALIZED IMMUNITY TO THE LARGE ROUNDWORM ASCARIS SUUM IN SWINE - (Proceedings)

Solano Aguilar, G., Beshah, E., Motoko, M., Schoene, N.W., Urban Jr, J.F. 2001. Localized immunity to the large roundworm ascaris suum in swine. Proceedings of Allen D Leman Swine Conference.

CYTOKINE AND LYMPHOCYTE PROFILE AFTER ORAL INFECTION WITH TOXOPLASMA GONDIOOCYSTS IN MINIATURE SWINE - (Abstract Only) - (02-Jul-01)

CYTOKINE AND LYMPHOCYTE PROFILE IN MINIATURE SWINE AFTER ORAL INFECTION WITH TOXOPLASMA GONDII OOCYSTS - (Abstract Only) - (15-Jun-01)

CYTOKINE AND LYMPHOCYTE PROFILE IN MINIATURE SWINE AFTER ORAL INFECTION WITH TOXOPLASMA GONDII OOCYSTS - (Peer Reviewed Journal)

Solano Aguilar, G., Beshah, E., Vengroski, K.G., Zarlenga, D.S., Jauregui, L., Cosio, M., Douglass, L.W., Dubey, J.P., Lunney, J.K. 2001. Cytokine and lymphocyte profile in miniature swine after oral infection with toxoplasma gondii oocysts. International Journal for Parasitology. vol. 31, pp. 187-95.

ISOLATION AND PURIFICATION OF LYMPYHOCYTE SUBSETS FROM GUT ASSOCIATED LYMPHOID TISSUE IN NEONATAL SWINE - (Peer Reviewed Journal) - (25-Apr-00)

CHARACERIZATION OF LYMPHOID POPULATIONS FROM MUCOSAL TISSUES OF NEONATAL PIGS - (Peer Reviewed Journal) - (17-Dec-99)

SWINE IMMUNE RESPONSE TO TOXOPLASMA GONDII INFECTIONS AND TO VACCINATION WITH IRRADIATED OOCYSTS - (Abstract Only) - (22-Oct-98)

MUCOSAL IMMUNE RESPONSES IN NEONATAL SWINE - (Proceedings) - (15-Sep-98)

TOXOPLASMOSIS IN SWINE: VACCINATION AND PROTECTIVE IMMUNITY - (Abstract Only) - (15-Aug-98)

CHARACTERIZATION OF GENES CONTROLLING PROTECTIVE IMMUNE RESPONSES TO TOXOPLASMA GONDII INFECTION OF PIGS - (Abstract Only) - (08-Aug-98)

CHARACTERIZATION OF PROTECTIVE IMMUNE RESPONSE IN PIGS AFTER TOXOPLASMA GONDII INFECTION. - (Abstract Only) - (20-May-98)

CHARACTERIZATION OF PROTECTIVE IMMUNE RESPONSE IN PIGS AFTER TOXOPLASMA GONDII INFECTION - (Proceedings) - (15-Feb-98)