Project Number: 6612-42000-012-01
Project Type: Reimbursable

Start Date: Sep 27, 2010
End Date: Aug 31, 2013

Objective:
Determine the role of fumonisin exposure in the high incidence of neural tube defects (NTDs) in consumers of maize products.

Approach:
Utilize information developed from Creighton University studies in mouse models to assess and validate the use of sphingolipid and genetic mechanism-based and fumonisin exposure-based biomarkers in women from populations known to consume large amounts of maize potentially contaminated with fumonisin.