ARS | Publication request: Evolutionary sequenomics: The utility of comparative chromosomal synteny searches in revealing homologous DNA blocks derived from fish-specific 3R- and 4R-genome duplications

Submitted to: Meeting Abstract
Publication Type: Abstract Only
Publication Acceptance Date: May 17, 2007
Publication Date: N/A

Technical Abstract: Most Actinopterygian fishes are believed to have arisen from a whole genome duplication approximately 275-350 MYA (3R duplication). Within the teleosts, several orders possess additional species that have undergone either an additional whole genome autopolyploid duplication (4R duplication), or are derived from allopolyploid hybridization events. Salmonid fishes are an ordinal example of a 4R derivative lineage within the basal teleost fishes. To date, we have identified the majority of the homeologous (duplicated homologous) linkage groups in three model species (rainbow trout, Arctic charr, and Atlantic salmon) within this order. In rainbow trout, 25-26 homeologues are expected, given the NF ranges from 100-104. We describe our findings from a comparative BLASTN synteny search using type I gene and type II anonymous markers in the rainbow trout linkage map to nearly completed teleost sequenomes (e.g. zebrafish), that relate duplicated 3R segments to their 4R paralogues in rainbow trout.