ARS | Publication request: Cellular and Molecular Interactions of Rhabdoviruses with their Insect and Plant Hosts

Submitted to: Annual Review Of Entomology
Publication Type: Review Article
Publication Acceptance Date: July 29, 2008
Publication Date: January 1, 2009
Repository URL: http://hdl.handle.net/10113/22217
Citation: El-Desouky, A., Chi-Wei, T., Whitfield, A.E., Redinbaugh, M.G., Hogenhout, S.A. 2009. Cellular and Molecular Interactions of Rhabdoviruses with their Insect and Plant Hosts. Annual Review Of Entomology. 54:447-468.

Technical Abstract: The rhabdoviruses form a large family (Rhabdoviridae) whose host ranges include humans, other vertebrates, invertebrates, and plants. There are about 75 plant-infecting rhabdoviruses described, several of which are economically important pathogens that are persistently transmitted to their plant hosts only by insect vectors, particularly aphids, leafhoppers and planthoppers. Additionally, many vertebrate-infecting rhabdoviruses are biologically transmitted by hematophagous insects. Rhabdoviruses replicate in their insect hosts, and each virus is normally transmitted only by one or a few related vector species. In this review, we provide an overview of propagative transmission of plant rhabdoviruses, as compared to vertebrate-infecting viruses and with the Sigma rhabdovirus infecting Drosophila. We also focus on recent advances in studying cellular and molecular aspects of vector/host specificity, route of virus infection in insects, transmission barriers and virus receptors in the vectors, insect response to virus infection and, for plant rhabdoviruses, comparison between virus infection of plant and insect cells.